5,690 research outputs found
L’évolution d’une coopération bibliothéconomique dans le secteur de la santé: le consortium des ressources électroniques du RUIS de l’UdeM
Sous l’impulsion de la Loi 83, loi modifiant la Loi sur les services de santé et les services sociaux et d’autres dispositions législatives, sanctionnée en 2005, et fort d’une expérience issue d’une coopération de plus de 30 ans entre les bibliothèques des sciences de la santé de l’Université de Montréal et les bibliothèques de ses hôpitaux affiliés, un consortium est né ayant pour but de regrouper les efforts et augmenter l’offre documentaire pour mieux desservir ses clientèles.
Après avoir décrit quelques consortiums canadiens dans le domaine de la santé, les auteurs présentent le nouveau consortium des ressources électroniques du Réseau universitaire intégré de santé de l’Université de Montréal (RUISUM)qui s’est vu confié le mandat de procurer des ressources informationnelles en sciences de la santé ainsi que des services afin de mieux soutenir l’enseignement, la recherche, la formation professionnelle continue et le soutien à la démarche clinique dans les établissements membres. Le territoire desservi par le RUIS de l’Université couvre un bassin de population de 3 millions d’habitants, représente 40% des soins de la santé de la province et s’adresse à plus de 25 000 professionnels de la santé.
Dans le respect des stratégies de chaque établissement membre, le consortium du RUISUM a redéfinit le couple produit marché pour se positionner dans le segment des bibliothèques virtuelles. Il met l’accent sur la formation aux compétences informationnelles, sur l’interaction avec le personnel de la bibliothèque et utilise le web comme outil
Quantifying precision and accuracy of measurements of dissolved inorganic carbon stable isotopic composition using continuous-flow isotope-ratio mass spectrometry
RATIONALE:
We describe an analytical procedure that allows sample collection and measurement of carbon isotopic composition (δ13CV-PDB value) and dissolved inorganic carbon concentration, [DIC], in aqueous samples without further manipulation post field collection. By comparing outputs from two different mass spectrometers, we quantify with the statistical rigour uncertainty associated with the estimation of an unknown measurement. This is rarely undertaken, but it is needed to understand the significance of field data and to interpret quality assurance exercises.<p></p>
METHODS:
Immediate acidification of field samples during collection in evacuated, pre-acidified vials removed the need for toxic chemicals to inhibit continued bacterial activity that might compromise isotopic and concentration measurements. Aqueous standards mimicked the sample matrix and avoided headspace fractionation corrections. Samples were analysed using continuous-flow isotope-ratio mass spectrometry, but for low DIC concentration the mass spectrometer response could be non-linear. This had to be corrected for.<p></p>
RESULTS:
Mass spectrometer non-linearity exists. Rather than estimating precision as the repeat analysis of an internal standard, we have adopted inverse linear calibrations to quantify the precision and 95% confidence intervals (CI) of the δ13CDIC values. The response for [DIC] estimation was always linear. For 0.05–0.5 mM DIC internal standards, however, changes in mass spectrometer linearity resulted in estimations of the precision in the δ13CVPDB value of an unknown ranging from ± 0.44‰ to ± 1.33‰ (mean values) and a mean 95% CI half-width of ±1.1–3.1‰.<p></p>
CONCLUSIONS:
Mass spectrometer non-linearity should be considered in estimating uncertainty in measurement. Similarly, statistically robust estimates of precision and accuracy should also be adopted. Such estimations do not inhibit research advances: our consideration of small-scale spatial variability at two points on a small order river system demonstrates field data ranges larger than the precision and uncertainties. However, without such statistical quantification, exercises such as inter-lab calibrations are less meaningful.<p></p>
Optimal skeleton huffman trees revisited
A skeleton Huffman tree is a Huffman tree in which all disjoint maximal perfect subtrees are shrunk into leaves. Skeleton Huffman trees, besides saving storage space, are also used for faster decoding and for speeding up Huffman-shaped wavelet trees. In 2017 Klein et al. introduced an optimal skeleton tree: for given symbol frequencies, it has the least number of nodes among all optimal prefix-free code trees (not necessarily Huffman’s) with shrunk perfect subtrees. Klein et al. described a simple algorithm that, for fixed codeword lengths, finds a skeleton tree with the least number of nodes; with this algorithm one can process each set of optimal codeword lengths to find an optimal skeleton tree. However, there are exponentially many such sets in the worst case. We describe an (formula presented)-time algorithm that, given n symbol frequencies, constructs an optimal skeleton tree and its corresponding optimal code. © Springer Nature Switzerland AG 2020.Supported by the Russian Science Foundation (RSF), project 18-71-00002
Expansion of magnetic clouds in the outer heliosphere
A large amount of magnetized plasma is frequently ejected from the Sun as
coronal mass ejections (CMEs). Some of these ejections are detected in the
solar wind as magnetic clouds (MCs) that have flux rope signatures. Magnetic
clouds are structures that typically expand in the inner heliosphere. We derive
the expansion properties of MCs in the outer heliosphere from one to five
astronomical units to compare them with those in the inner heliosphere. We
analyze MCs observed by the Ulysses spacecraft using insitu magnetic field and
plasma measurements. The MC boundaries are defined in the MC frame after
defining the MC axis with a minimum variance method applied only to the flux
rope structure. As in the inner heliosphere, a large fraction of the velocity
profile within MCs is close to a linear function of time. This is indicative
of} a self-similar expansion and a MC size that locally follows a power-law of
the solar distance with an exponent called zeta. We derive the value of zeta
from the insitu velocity data. We analyze separately the non-perturbed MCs
(cases showing a linear velocity profile almost for the full event), and
perturbed MCs (cases showing a strongly distorted velocity profile). We find
that non-perturbed MCs expand with a similar non-dimensional expansion rate
(zeta=1.05+-0.34), i.e. slightly faster than at the solar distance and in the
inner heliosphere (zeta=0.91+-0.23). The subset of perturbed MCs expands, as in
the inner heliosphere, at a significantly lower rate and with a larger
dispersion (zeta=0.28+-0.52) as expected from the temporal evolution found in
numerical simulations. This local measure of the expansion also agrees with the
distribution with distance of MC size,mean magnetic field, and plasma
parameters. The MCs interacting with a strong field region, e.g. another MC,
have the most variable expansion rate (ranging from compression to
over-expansion)
Crying and feeding problems in infancy and cognitive outcome in preschool children born at risk : a prospective population study
Objective: To investigate whether regulatory problems, i.e., crying and feeding problems in infants > 3 months of age, predict cognitive outcome in preschool children born at risk even when controlled for confounding factors.
Methods: A prospective longitudinal study of children born in a geographically defined area in Germany. N = 4427 children of 6705 eligible survivors (66%) participated at all four assessment points (neonatal, 5, 20, and 56 months of age). Excessive crying and feeding problems were measured at 5 months. Mental development was assessed with the Griffiths Scale at 20 months, and cognitive assessments were conducted at 56 months. Neonatal complications, neurological, and psychosocial factors were controlled as confounders in structural equation modeling and analyses of variance.
Results: One in five infants suffered from single crying or feeding problems, and 2% had multiple regulatory problems, i.e., combined crying and feeding problems at 5 months. In girls, regulatory problems were directly predictive of lower cognition at 56 months, even when controlled for confounders, whereas in boys, the influence on cognition at 56 months was mediated by low mental development at 20 months. Both in boys and girls, shortened gestational age, neonatal neurological complications, and poor parent-infant relationship were predictive of regulatory problems at 5 months and lower cognition at 56 months.
Conclusion: Regulatory problems in infancy have a small but significant adverse effect on cognitive development
Diagonal ear lobe crease in diabetic south Indian population: Is it associated with Diabetic Retinopathy?. Sankara Nethralaya Diabetic Retinopathy Epidemiology And Molecular-genetics Study (SN-DREAMS, Report no. 3)
<p>Abstract</p> <p>Background</p> <p>To report the prevalence of ear lobe crease (ELC), a sign of coronary heart disease, in subjects (more than 40 years old) with diabetes and find its association with diabetic retinopathy.</p> <p>Methods</p> <p>Subjects were recruited from the Sankara Nethralaya Diabetic Retinopathy Epidemiology And Molecular-genetics Study (SN-DREAMS), a cross-sectional study between 2003 and 2006; the data were analyzed for the1414 eligible subjects with diabetes. All patients' fundi were photographed using 45° four-field stereoscopic digital photography. The diagnosis of diabetic retinopathy was based on the modified Klein classification. The presence of ELC was evaluated on physical examination.</p> <p>Results</p> <p>The prevalence of ELC, among the subjects with diabetes, was 59.7%. The ELC group were older, had longer duration of diabetes, had poor glycemic control and had a high socio-economic status compared to the group without ELC and the variables were statistically significant. There was no statistical difference in the prevalence of diabetic retinopathy in two groups. On multivariate analysis for any diabetic retinopathy, the adjusted OR for women was 0.69 (95% CI 0.51-0.93) (p = 0.014); for age >70 years, 0.49 (95% CI 0.26-0.89) (p = 0.024); for increasing duration of diabetes (per year increase), 1.11(95% CI 1.09-1.14) (p < 0.0001); and for poor glycemic control (per unit increase in glycosylated heamoglobin), 1.26 (95% CI 1.19-1.35) (p < 0.0001). For sight-threatening diabetic retinopathy, no variable was significant on multivariable analysis. In predicting any diabetic retinopathy, the presence of ELC had sensitivity of 60.4%, and specificity, 40.5%. The area under the ROC curve was 0.50 (95% CI 0.46-0.54) (p 0.02).</p> <p>Conclusion</p> <p>The ELC was observed in nearly 60% of the urban south Indian population. However, the present study does not support the use of ELC as a screening tool for both any diabetic retinopathy and sight-threatening retinopathy.</p
From Predicting Solar Activity to Forecasting Space Weather: Practical Examples of Research-to-Operations and Operations-to-Research
The successful transition of research to operations (R2O) and operations to
research (O2R) requires, above all, interaction between the two communities. We
explore the role that close interaction and ongoing communication played in the
successful fielding of three separate developments: an observation platform, a
numerical model, and a visualization and specification tool. Additionally, we
will examine how these three pieces came together to revolutionize
interplanetary coronal mass ejection (ICME) arrival forecasts. A discussion of
the importance of education and training in ensuring a positive outcome from
R2O activity follows. We describe efforts by the meteorological community to
make research results more accessible to forecasters and the applicability of
these efforts to the transfer of space-weather research.We end with a
forecaster "wish list" for R2O transitions. Ongoing, two-way communication
between the research and operations communities is the thread connecting it
all.Comment: 18 pages, 3 figures, Solar Physics in pres
The polarization observables T, P, and H and their impact on multipoles
Data on the polarization observables T, P, and H for the reaction are reported. Compared to earlier data from other experiments, our
data are more precise and extend the covered range in energy and angle
substantially. The results were extracted from azimuthal asymmetries measured
using a transversely polarized target and linearly polarized photons. The data
were taken at the Bonn electron stretcher accelerator ELSA with the CBELSA/TAPS
detector. Within the Bonn-Gatchina partial wave analysis, the new polarization
data lead to a significant narrowing of the error band for the multipoles for
neutral-pion photoproduction
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